|Latest Research on Tissue Engineering|
|Scientists create tiny, biodegradable scaffold to
transplant stem cells and deliver drugs|
Rutgers scientists have created a tiny, biodegradable scaffold
to transplant stem cells and deliver drugs, which may help treat Alzheimer's
and Parkinson's diseases, aging brain degeneration, spinal cord injuries and
traumatic brain injuries.
Stem cell transplantation, which shows promise as a treatment
for central nervous system diseases, has been hampered by low cell survival
rates, incomplete differentiation of cells and limited growth of neural
connections.
It's been a major challenge to develop a reliable therapeutic method for
treating central nervous system diseases and injuries," said study senior
author KiBum Lee, a professor in the Department of Chemistry and Chemical
Biology at Rutgers University-New Brunswick. "Our enhanced stem cell
transplantation approach is an innovative potential solution."
The researchers, in cooperation with neuroscientists and clinicians,
plan to test the nano-scaffolds in larger animals and eventually move to
clinical trials for treating spinal cord injury. The scaffold-based technology
also shows promise for regenerative medicine.
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